• Glehnia and Rehmannia Combination (Yi Guan Jian)

By Kan Essentials

Glehnia and Rehmannia Combination (Yi Guan Jian)

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Yi Guan Jian is a classical formula traditionally used to nourish Liver and Stomach Yin while regulating constrained Liver Qi in patterns of chronic depletion with secondary tension or irritation.

In veterinary practice, it is particularly useful in animals showing dryness, irritability, gastrointestinal inflammation or ulcer tendency where depletion and tension coexist rather than purely excess inflammatory Heat or Damp accumulation.

This formula is commonly selected in animals showing chronic irritation, dryness, tension or ulcer tendency where depletion and constraint coexist — even when the patient does not appear overtly weak or deficient.

Unlike richer Blood-tonifying formulas, Yi Guan Jian restores fluids and nourishment while remaining relatively light and non-cloying, making it particularly useful in modern inflammatory or stress-sensitive patients where stronger tonification may aggravate stagnation or Dampness.

 


Currently in Australia, KAN herbal blends are only allowed to be dispensed by a registered veterinarian.

As with all Traditional Chinese Herbal blends, KAN Herbs are best prescribed by an integrative veterinarian who can examine your animal in person. Telehealth consultations however can be used when access to an appropriate veterinarian is difficult or not possible.

If you are a registered Veterinarian, please get in touch via our contact page.

If you would like to access the KAN range of herbal blends, please book an appointment to access a telehealth (phone or video) appointment with Dr Tanya Meares BVSc.

Before the appointment, you will be asked to submit a form with background information about your animal and their health issues.

The cost of the 30 minute telehealth appointment is $80 but you will receive a discount of $40 on your first order of any product product in the shop.

These formulas require practitioner dispensing under current regulatory guidelines.

How it Works

Yi Guan Jian is a classical formula traditionally used to nourish Yin and Blood in animals showing chronic dryness, irritation and tension associated with depletion.

In Traditional Chinese Medicine, prolonged stress, chronic inflammation, overwork or persistent irritation may gradually consume Yin and fluids. As depletion develops, tissues become less resilient and more prone to dryness, irritation, tension and inflammatory sensitivity.

Unlike Damp-Heat patterns, where inflammation is associated with heaviness, moisture or congestion, Yi Guan Jian is more appropriate where inflammation develops alongside dryness, depletion or tissue irritation.

This formula is particularly useful in animals that remain reactive, tense or ulcer-prone despite lacking obvious excess Heat or Damp accumulation.

Clinically, this formula is commonly used in:

  • chronic gastritis or acid regurgitation
  • ulcer-prone horses
  • hyperthyroid cats with irritability and weight loss
  • dry inflammatory bowel patterns
  • chronic vomiting in tense or depleted animals
  • stress-associated gastrointestinal irritation
  • dry, irritated inflammatory conditions
  • chronic inflammatory states where depletion and tension coexist

Animals suited to this formula often show:

  • irritability or tension layered over depletion
  • weight loss despite maintained appetite
  • dry tissues or reduced resilience
  • gastrointestinal irritation without marked Dampness
  • stress sensitivity
  • intermittent inflammatory flare without strong greasy or boggy signs

Unlike richer Blood-tonifying formulas, Yi Guan Jian restores fluids and nourishment while remaining relatively light and non-cloying, making it particularly useful in modern inflammatory or stress-sensitive patients where stronger tonification may aggravate stagnation or Dampness.

In Western physiological terms, this formula is often used in animals showing chronic inflammatory irritation alongside tissue depletion, dryness or stress-related dysregulation.

Think: chronic dryness, irritation and depletion with secondary tension or constraint.

This formula is generally less appropriate where:

  • strong Damp-Heat or greasy inflammatory patterns predominate
  • marked mucus accumulation or boggy inflammation are present
  • severe Cold or deficient circulation patterns dominate.
Ingredients

Raw rehmannia root
Lycium fruit
Dang Gui root
Ophiopogon tuber
Glehnia root


Melia fruit
Dosing
4kg give 0.3mls twice daily
8kg give 0.45mls twice daily
12kg give 0.60mls twice daily
23kg give 0.9mls twice daily
32kg give 1.2mls twice daily
75kg give 1.8mls twice daily
Shipping

We currently ship only to Australia. Contact us if you are in NZ and interested in getting our products.  (Not Canada or USA)

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Frequently Asked Questions

Can Yi Guan Jian help ulcer-prone horses or dogs?

Yes. In integrative veterinary practice, Yi Guan Jian is commonly used in ulcer-prone animals showing chronic tension, irritation or gastrointestinal sensitivity, particularly where stress and depletion appear to contribute to ongoing symptoms.
Why do some animals develop dryness and irritation rather than “Damp” inflammation?

In some chronically stressed or inflamed animals, prolonged irritation gradually consumes Yin and body fluids.

As tissues lose moisture and resilience, inflammation may begin presenting as dryness, irritation, tension or ulcer tendency rather than greasy, boggy or heavily congested Damp patterns.
Can this formula be used in animals with chronic kidney disease or ageing-related decline?

Yes. In Traditional Chinese Medicine, Yin deficiency patterns are commonly associated with ageing, chronic depletion and reduced fluid resilience.

Clinically, Yi Guan Jian is sometimes used in older animals showing dryness, weight loss, irritability, cognitive decline or chronic inflammatory irritation alongside renal disease or age-related depletion.
Can Yi Guan Jian be used in anxious or highly reactive animals?

Yes. This formula is often useful in animals where chronic tension, irritability or stress sensitivity coexist with gastrointestinal irritation, dryness or depletion.

These animals may appear reactive or “wired,” yet simultaneously show signs of reduced resilience or chronic inflammatory exhaustion underneath.
Can this formula help animals recovering from chronic illness, anaemia or autoimmune disease?

Yi Guan Jian is sometimes used in chronically depleted animals recovering from prolonged illness, inflammatory disease, autoimmune disease or blood loss, particularly where dryness, irritation or poor tissue resilience persist during recovery.

In integrative practice, Rehmannia-containing formulas are also traditionally used to support Blood and marrow restoration in depleted or chronically inflamed patients.